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Methyl fluorosulfonate : ウィキペディア英語版 | Methyl fluorosulfonate
|Section2= |Section3= }} Methyl fluorosulfonate, (also known as magic methyl, a name coined by George Olah) has the chemical formula F-SO2-OCH3. It is prepared by distillation of an equimolar mixture of fluorosulfonic acid and dimethyl sulfate, and used as a powerful methylating reagent (about four orders of magnitude more reactive than methyl iodide). Since it will just as readily methylate biological tissues, it is acutely toxic (LC50 (rat) ~ 5 ppm), causing irritation of the airways and pulmonary edema, presumably by methylation of lipids in the cell membranes. Its use as a methylating reagent is banned by many organisations as a result. ==References== 〔
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